Curators' Distinguished Professor and Keith and Pat Bailey Distinguished Professor
Mechanical and Aerospace Engineering
Research Interests:
Additive Manufacturing, Rapid Prototyping, CAD/CAM, Intelligent Robotics, Artificial Intelligence, Machine dynamics and Control, Modeling and Simulation, Design and Manufacturing Automation, Virtual and Augmented Reality
Publications:
Resume/CV:
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INVESTIGATORS
Ming Leu (mleu@mst.edu, 573-341-4482), Julie Semon, Delbert Day, Krishna Kolan, Caroline Murphy
FUNDING SOURCE
Missouri Research Board, MO-SCI Corporation, Intelligent Systems Center (Missouri S&T), Keith and Pat Bailey Professorship Fund (Missouri S&T)
PROJECT DESCRIPTION
In this research, we first investigated the fabrication of scaffolds with engineered porosity from 13-93 bioactive glass using the selective laser sintering (SLS) process and an extrusion-based process. The SLS process is a powder-bed based additive manufacturing technique that fabricates a scaffold layer-by-layer by controlling laser scans to sinter the mixture of ceramic and binder particles in a powder bed. Pore geometry in the scaffold is shown to play a crucial role as it affects not only the mechanical properties and degradation over time as well as the amount of bone regeneration upon implantation. In the extrusion-based process, aqueous-based bioactive glass paste was deposited layer-by-layer using a micro-sized nozzle. The fabricated green scaffolds are then heat treated to remove the binder. Our sintered scaffolds demonstrated an average compressive strength of 136 MPa, which is the highest reported in additive manufacturing of bioactive glass. To improve the toughness of the scaffold, titanium fibers were added to the paste to increase the fracture toughness and flexure strength of the scaffold.
Because a major limitation of synthetic bone repair is insufficient vascularization in the interior of the porous implant, our current research focuses on 3D bioprinting of mesenchymal stem cells (MSCs) suspended in the hydrogel and polymer-bioactive glass composite. Bioprinting a scaffold with these materials would offer a 3D environment for complex and dynamic interactions that govern the MSCs behavior in vivo. Bioactive glass is added to a mixture of polymer and an organic solvent to make an extrudable paste. Porous polymer-glass composite scaffolds are fabricated by extruding this paste using a syringe, and MSCs suspended in the hydrogel is deposited using another syringe. In vitro assessment indicates the viability of the process to print MSCs suspended in Matrigel. Fluorescence images from the live-dead assay indicate that cells are alive and actively moving in the scaffold.
SELECTIVE PUBLICATIONS
INVESTIGATORS
Ming Leu (mleu@mst.edu, 573-341-4482), Frank Liu, Maggie Cheng, Rakib Shahriar, Nahian Al Sunny, Liwen Hu
FUNDING SOURCE
National Science Foundation
PROJECT DESCRIPTION
This is a collaborative research project between Missouri S&T and the University of Arkansas. This project is dedicated to the development of a framework including architecture and protocols for communication among various manufacturing resources and management of manufacturing services for cyber-physical systems in cloud manufacturing. The practical aim is of the cyber-physical system to increase the productivity and efficiency of industrial enterprises by managing and sharing geographically dispersed manufacturing resources and connecting customers with manufacturing companies. The research consists of the following tasks: 1) scalable service-oriented architecture for scalable cyber-physical manufacturing, 2) network architecture and plug-and-play protocols, 3) methods for virtualization of manufacturing resources (e.g., CNC machines, 3D printers, CMMs), and 4) development of a testbed to evaluate the developed architecture, protocols, and methods.
SELECTIVE PUBLICATIONS
INVESTIGATORS
Ming Leu (mleu@mst.edu, 573-341-4482), Joseph Newkirk, Frank Liou, Edward Kinzel, Robert Landers, Douglas Bristow, Lianyi Chen, Ronald O’Malley, Tarak Amine, Austin Sutton, Caitlin Kriewall, Sreekar Karnati, Zachary Hilton, Li Lan, Baily Thomas, Daniel Jacob, Izach Axelsen, Kimberly Dyhouse, Matthew Guile, Nick Pashos, Cody Lough, Benjamin Rackers
FUNDING SOURCE
Honeywell Federal Manufacturing & Technologies
PROJECT DESCRIPTION
The aim of this project is to perform fundamental research aimed at understanding the selective laser melting (SLM) process, which is an additive manufacturing technique that bonds successive layers of powder to produce metal parts with any complex 3D geometry. The main research objectives are: to characterize powder material, relate it to part properties and assess its viability for reuse/recycling; to improve part properties through optimization of process parameters; to control the microstructure of manufactured parts with sensing using an infrared camera; to tune the chemistry of input powder for the SLM process. To address these objectives, the project consists of the following tasks: 1) powder characterization, 2) material property characterization, 3) temperature effects on material properties, 4) controlling microstructure and mechanical properties, and 5) chemistry specifically for additive manufacturing.
SELECTIVE PUBLICATIONS
INVESTIGATORS
Ming C. Leu (mleu@mst.edu), 573-341-4482, Greg E. Hilmas, Jeremy L. Watts, Amir Ghazanfari, Wenbin Li, Devin McMillen
FUNDING SOURCE
Department of Energy (National Energy Technology Laboratory), Intelligent Systems Center (Missouri S&T)
PROJECT DESCRIPTION
This research investigates using the ceramic on-demand extrusion (CODE) process to fabricate complex 3D parts made of ceramics and ceramic composites, with applications to aerospace, energy, and biomedical industries. CODE is a novel freeform extrusion fabrication process recently developed at Missouri S&T. This process uses layer-by-layer extrusion of aqueous pastes followed by uniform radiation drying between successive layers. The parts that we have fabricated using this process include aerospace structural components with high-temperature and ultra-high-temperature materials (e.g., alumina, zirconium diboride, and partially stabilized zirconia). This process has also been used to fabricate smart parts with embedded sensors, e.g., smart lining blocks with embedded optical fiber sensors that can used for in situ temperature and stress monitoring. Our current research focuses on fabricating composite structures made of two or more materials that can be distinct materials or graded in compositions continuously as programmed to created parts with functionally graded materials. The current research tasks include: (1) design of parts with optimal material distribution, (2) development of colloidal pastes from ceramic powder (3) simultaneous control of flow rates of multiple pastes and homogeneous mixing of pastes, and (4) evaluating the mechanical properties of fabricated parts with functionally graded materials.
SELECTIVE PUBLICATIONS
INVESTIGATORS
Ming Leu (mleu@mst.edu, 573-341-4482), K. Chandrashekhara, Leah Mason, Greg Taylor, Xin Wang, Mike Matlack, James Castle
FUNDING SOURCE
Boeing, Stratasys, and Steelville Manufacturing (via the Center for Aerospace Manufacturing Technologies at Missouri S&T), America Makes
PROJECT DESCRIPTION
The objective of this research project is to investigate low-cost rapid tooling with Ultem (9085 & 1010) using the fused deposition modeling (FDM) process, an additive manufacturing technique that built a part layer-by-layer by extruding thermoplastic material that is supplied in the filament form. The tooling can be used in manufacturing of composites with the autoclave, vacuum assisted resin transfer molding and other processes, as well as in stamp forming applications. In this project, Ultem specimens are fabricated using the FDM process and then their mechanical properties are measured in compression, tension, and flexure tests at room and elevated temperatures. The test specimens include solid coupons and sparse-build coupons with varying build parameters including air gap, wall thickness, and cap thickness, as well as different internal lattice structures. Modeling and simulation with finite element analysis is used to predict the mechanical properties of sparse-build FDM tools and compare the predicted results with data obtained from experimental testing. The project is conducted jointly by Missouri S&T and Boeing Research & Technology.
SELECTIVE PUBLICATIONS
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